RESEARCH ARTICLE


Is Penile Shortening Part of Natural History of Peyronie's Disease?



Sudhanshu Chitale*, Mohammed Morsey , Krishna Sethia
Department of Urology, Norfolk & Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY, UK


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open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Urology, Norfolk & Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY, UK; Tel: 00441603286776; Fax: 00441603287884;Emails: chitalenorwich@aol.comsudhanshu.chitale@nnuh.nhs.uk


Abstract

Introduction/Aims:

We have studied the natural history of Peyronie’s disease with particular reference to erect (functional) penile length. To our knowledge this has so far not been documented.

Methods:

21 men with stable Peyronie’s deformity were followed up for 6 months when no active treatment was being offered. By inducing an artificial erection objective assessments of penile length and deformity were made on day 1 and at six months.

Results:

Measurable shortening in straight penile length was noticed in 6/21 (28.5%) of men (Mean: 0.92 cm), lengthening in 8/21 (38.09%) of men (Mean: 0.81 cm), while no change was noticed in the remaining 7 (33.3%).

Angulation increased (worsened) in 5 (23.8%), decreased (improved) in 11 (52.38%) and showed no change in 5 (23.8%). There was no association between change in angle of deformity and change in penile length.

CONCLUSIONS:

In Peyronie’s disease, a progressive reduction in penile length is noticed in up to a third of patients with stable disease and this is not necessarily associated with deteriorating angle of deformity.

Keywords : Peyronie’s disease, Natural history, functional length..