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The Pathophysiology of Antiphospholipid Syndrome
The Open Urology & Nephrology Journal
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20 Feb 2015 •
RESEARCH ARTICLE
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DOI: 10.2174/1874303X01508010002
Abstract
Advances in our knowledge of the pathogenic mechanisms of antiphospholipid syndrome have been achieved in the past few years. Apart from the well-known role of anti-β2-glycoprotein I antibodies, complement, endocrine and genetic factors and a variety of other molecules are now under investigation. These new approaches should lead to novel explanations and potential new treatment options.
Keywords: Anti-β2-glycoprotein, antiphospholipid syndrome, antiphospholipid antibodies, complement.