RESEARCH ARTICLE
LEARNING FROM IMAGES : Vascular Extension from an Infiltrating Renal Tumor
Manoj Ketkar* , 1, Tushar J. Vachharajani2, Pramod Gupta1
Article Information
Identifiers and Pagination:
Year: 2012Volume: 5
First Page: 48
Last Page: 49
Publisher ID: TOUNJ-5-48
DOI: 10.2174/1874303X01205010048
Article History:
Received Date: 24/10/2012Revision Received Date: 9/11/2012
Acceptance Date: 11/11/2012
Electronic publication date: 14/12/2012
Collection year: 2012

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
61-year-old male patient presented with chief complaints of recurrent right renal colic and hematuria.
A ‘stone protocol’ non contrast CT scan of the abdomen and pelvis was performed, which revealed hyperdense blood in the pelvicalyceal system (Fig. 1A) and blood clots in the bladder (not shown). A contrast enhanced CT scan of the abdomen and pelvis (Fig. 1B) revealed an infiltrative lesion involving the pelvicalyceal system of the right kidney with thrombosis of the right renal vein. Coronal T1 weighted post contrast MRI image (Fig. 2) revealed an infiltrative mass involving the right kidney with notable absence of caliectasis or hydronephrosis. Thrombus involving the right renal vein and the inferior vena cava was seen as a filling defect. The microscopic examination of the surgical specimen revealed clear cell type renal cell cancer, with tumor extending into the right renal vein and its walls. On surgical exploration, tumor invasion of the renal capsule with extension into the perinephric fat but restricted to Gerota’s fascia was seen.
Neoplasms account for a significant number of infiltrative renal lesions seen on imaging studies and include a variety of uncommon tumors such as renal medullary carcinoma. However, infiltrative growth is an atypical manifestation (6% of cases) of commonly encountered renal cell carcinoma [1].
The more common subtypes of renal cell cancer -clear cell, papillary, and chromophobe cell-typically appear as well-defined mass and may form a capsule of connective tissue and compressed atrophic renal parenchyma with tumor proliferation. Occasionally, the tumor appears ill-defined and infiltrative; this appearance is more typical of the uncommon sarcomatoid subtype but may be seen with the other subtypes as well.
Absence of caliectasis is usually a clue to the diagnosis of renal cell cancer over transitional cell cancer. However renal vein invasion can occur in both types of carcinoma.
CONFLICT OF INTEREST
The authors confirm that this article content has no conflict of interest.
ACKNOWLEDGEMENTS
Declared none.